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KMID : 0387820020090010117
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Clinical Pediatric Hematology-Oncology
2002 Volume.9 No. 1 p.117 ~ p.121
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An Isolated Relapse of Acute Lymphoblastic Leukemia as a Chest Wall Mass
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Lee Jee-Yeon
Lee Jung-Hwa
Song Dae-Jin
Woo Chan-Wook
Lee Kwang-Chul
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Abstract
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Extramedullary relapse of childhood acute lymphoblastic leukemia (ALL) occurs most commonly in the central nervous system or in the testes. Isolated relapse on chest wall as a soft tissue mass is extremely rare in children with ALL. We experenced a 12-year-old girl who developed an isolated relapse on chest wall during the treatment for ALL. She had a pain and protruding mass on right anterior chest wall 6 months after the initial diagnosis of ALL. Imaging study revealed an 5 7 cm sized soft tissue mass on the right chest wall. Histopathologic examination revealed infiltrates composed of immature lymphoblasts with morphology identical with that of previous bone marrow aspiration. Studies on bone marrow and cerebrospinal fluid were negative for disease at this time. The patient was treated with 3,000 cGy of local irradiation in 10 fractions and systemic chemotherapy with ifosfamide and etoposide. The mass size decreased markedly, but she has been suffering from development of multiple mass in other site and recurrent pleural effusion.
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KEYWORD
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Extramedullary relapse, Acute lymphoblastic leukemia
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